1. 圖1. 因2019冠狀病毒症(COVID-19：Coronavirus Disease-19)或流感住院的病患具有，在感染後18個月內，增加死亡、再入院及多個器官出現問題的風險。
Patients hospitalized with COVID-19 or flu have an increased risk of death, hospital readmission, and issues to multiple organs in the 18 months after infection.
Long-COVID, a condition in which the symptoms last for months after SARS-CoV-2 infection, affects approximately 10–20% of people. Researchers have now found a similar condition, called "long flu," wherein people hospitalized with seasonal influenza suffer long-term negative health effects.
在感染第二型嚴重急性呼吸系統徵候群-冠狀病毒(SARS-CoV-2：Severe Acute Respiratory Syndrome Coronavirus-2)後，症狀持續數月的一種疾病，長期-冠狀病毒症(COVID)影響約10-20%的人。目前，研究人員們已經發現一種，被稱為"長期流感"的類似疾病，因季節性流感住院者遭受長期的負面健康影響。
Researchers from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System compared various factors, including risks of death, hospital admissions and adverse health outcomes involving major organ systems, associated with the viruses causing flu and COVID-19.
來自美國聖路易斯市華盛頓大學醫學院，及聖路易斯退伍軍人事務部醫療保健體系的研究人員們比較了，包括與引起流感及COVID-19的病毒相關，涉及主要器官系統之死亡、住院及不良健康結果等風險的各種因素。
In both cases, patients hospitalized had an increased risk of death, hospital readmission and issues to multiple organs in the 18 months following the infection. The team also found that the risk was highest 30 days or later after the initial infection. The findings were published in the journal The Lancet Infectious Disease.在上述兩種病中，住院病患具有，在感染後18個月內，增加死亡、再入院及多個器官出現問題的風險。該團隊也發現，在最初感染後30天或更晚，風險最高。此些研究結果發，表於《柳葉刀傳染病》期刊。
"A review of past studies on COVID-19 versus the flu focused on a short-term and narrow set of health outcomes. Our novel approach compared the long-term health effects of a vast array of conditions. Five years ago, it wouldn't have occurred to me to examine the possibility of a 'long flu.' A major lesson we learned from SARS-CoV-2 is that an infection that initially was thought to only cause brief illness also can lead to chronic disease. This revelation motivated us to look at long-term outcomes of COVID-19 versus flu," senior author Dr. Ziyad Al-Aly, from Washington University, said in a news release.
在一則新聞稿中，來自華盛頓大學的資深撰文人，Ziyad Al-Aly博士宣稱：「過去針對COVID-19對照流感之諸多研究的縱覽，著重於短期及有限的一組健康結果上。我們的新方法比較了，極廣泛狀況對健康的長期影響。五年前，我不會想要調查 '長期流感'的可能性。我們從SARS-CoV-2，學到的一個重要教訓是，最初被認為只會引發短暫疾病的感染，也會導致慢性疾病。此新發現激發了我們，探究COVID-19對照流感的長期結果。」
Researchers evaluated 81,280 patients hospitalized for COVID-19 between March 2020 and June 2022, and 10,985 hospitalized for seasonal influenza between October 2015 and February 2019.
研究人員們評估了，在2020年3月至2022年6月期間，因COVID-19住院的81,280名病患，及2015年10月至2019年2月期間，因季節性流感住院的10,985名病患。
The researchers noted that a patient's vaccination status did not affect the results. Patients who had COVID-19 faced a 50% higher risk of death than those who had seasonal influenza during the 18 months of follow-up.
此些研究人員特別指出，病患的疫苗接種狀況，並不影響結果。在18個月的追蹤期間，罹患COVID-19的病患面臨了，比那些在追蹤之18個月期間，罹患季節性流感者，高出50%的死亡風險。
COVID-19 patients also had a higher rate of overall risk, hospital admissions and health issues to organ systems compared to those affected by seasonal influenza. However, the flu posed a higher risk to the pulmonary system than COVID-19.
相較於受季節性流感影響的病患，COVID-19病患具有，較高之整體風險、住院及對器官系統健康問題的比率。然而，流感對肺部系統構成了，比COVID-19更高的風險。
"This tells us the flu is truly more of a respiratory virus like we've all thought for the past 100 years. By comparison, COVID-19 is more aggressive and indiscriminate in that it can attack the pulmonary system, but it can also strike any organ system and is more likely to cause fatal or severe conditions involving the heart, brain, kidneys, and other organs," Al-Aly said.
Al-Aly宣稱：「這告知我們，流感確實更像是一種呼吸道病毒，就像我們過去100 年來，一直認為的那樣。相較之下，COVID-19更具攻擊性且無差別性，因為它會攻擊肺部系統。不過，它也會攻擊任何器官系統，且更有可能導致，涉及心臟、大腦、腎臟及其他器官之致命或嚴重的疾病。」
In both infections, the risk of death and disability occurred in the months after infection, not in the acute phase or the first 30 days.
在這兩種感染中，死亡及殘疾的風險，發生在感染後的幾個月內，而不是在急性期或最初30天。
"The study illustrates the high toll of death and loss of health following hospitalization with either COVID-19 or seasonal influenza. It's critical to note that the health risks were higher after the first 30 days of infection. Many people think they're over COVID-19 or the flu after being discharged from the hospital. That may be true for some people. But our research shows that both viruses can cause long-haul illness," Al-Aly said.
Al-Aly宣稱：「該研究明示了，因COVID-19或季節性流感住院後，高的死亡人數及健康損失。特別指出，健康風險在感染最初30天後較高，這是至關重要的。許多人認為，他們出院後渡過COVID-19或流感。對某些人而言，那可能是這樣。不過，我們的研究顯示，這兩種病毒皆會導致長期的疾病。」
網址：https://www.medicaldaily.com/long-flu-people-hospitalized-seasonal-influenza-may-suffer-negative-health-effects-similar-471196
翻譯：許東榮
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