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Gout

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Hyperuricemia male > 8 mg/dL, female > 7 mg/dL

Gout crystal
--長針狀,順黃垂監

Acute stage
1. NSAIDs
2. Colchicine - Stop if onset over 12 hrs, GI effect

Chronic stage
1. NSAIDs
2. colchicine for prevention from acute attack
3. 降尿酸:
---Allopurinol, 抑制production of uric acid, contraindicated in
combined use with Azathioprine
---Benzbromazone, 捉進尿酸排出, contraindicated in those who had
uric acid renal stone

2nd Gout

intefere with renal excretion of UA
--salycilate acid, nicotinic acid, Ethanol, Diuretics, Cyclosporine,
increased production
--lymphoproliferative, myeloproliferative, polythecemia, hemolysis
Others
--dehydration, starvation


Other crystal induced arthritis
1. CPPD
2. hydroxyapatite

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