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2010-06-30 09:29:43

SOCS1's protein structure and functional domain

ModBase Predicted Comparative 3D Structure on Q4JHT5Front Side Top There are two functional domains in SOCS1 protein, SH2 and SOCS C.this picture is originally from InterPro Domains.socs1 domain.png
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2010-06-30 00:21:31

SOCS1 is inclued in many pathways

Insulin resistance is strongly associated with type II diabetes. "Diabetogenic" factors including FFA, TNFalpha and cellular stress induce insulin resistance through inhibition of IRS1 functions. Seri...
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2010-06-29 23:55:55

Sequence similarity among the members

SOCS family protein sequence alignmentGenerated by CLC Sequence Viewer 6.4
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2010-06-29 23:32:49

Phylogenetics of SOCS family

NJ - 1.jpg
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2010-06-29 23:29:05

Homo sapiens SOCS Family Members

There are 7 members in this protein family.SOCS-1 O15524Name Suppressor of cytokine signaling 1 (SOCS-1) JAK-binding protein (JAB) STAT-induced STAT inhibitor 1 (SSI-1) Tec-interacting protein 3 (TIP-...
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2010-06-29 23:26:40

Homo sapiens suppressor of cytokine signaling gene family

SOCS (suppressor of cytokine signaling proteins) refers to a family of genes involved in inhibiting the Jak-STAT signaling pathway.one of the family members, SOCS1Preferred Namessuppressor of cytoki...
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